Pierre-Emmanuel Yoann N'Guetta

PhD Candidate


Curriculum vitae


Dept of Cell Biology & Physiology

UNC Chapel Hill School of Medicine



Pierre-Emmanuel Yoann N'Guetta

PhD Candidate


Contact

Pierre-Emmanuel Yoann N'Guetta

PhD Candidate


Curriculum vitae


Dept of Cell Biology & Physiology

UNC Chapel Hill School of Medicine




About Me


I am a developmental and cell biologist interested in studying neurovascular system and signaling during organogenesis to improve neurovascularization of engineered tissue to achieve better functionality in vivo.

I am currently a PhD candidate at the University of North Carolina at Chapel Hill, in the laboratory of Dr. Lori O’Brien, researching how renal nerve signaling impact kidney development.

I hope to complement my understanding of kidney development, neurovascular patterning and developmental biology with postdoctoral training that further my understanding of organoid differentiation and bioprinting methods aiming at recapitulating organ complex organisation and multicellular composition.

My predoctoral research is currently funded by a American Heart Association (AHA) Predoctoral Fellowship.


I am interested into the following questions:
  1. How do we establish the correct vascular network (artery, capillary, arteriole and vein) with the correct structural characteristics (vascular fenestration, mural cell coverage, etc) at the proper level in complex 3D engineered organ?
  2. How can we promote neo-innervation (i.e. precise growth of neural network) with functional nerve-cell crosstalk during organogenesis to ensure proper function, tissue assimilation, and bio-regulation post-implantation?
  3. How can we leverage signaling molecules from neuro-vascular system and promote proper tissue development and organization?
  4. How does extracellular matrix and mechanical force participates in proper morphogenesis in engineered organ?
Please do not hesitate to reach out if you want to connect or have any question.


Training:
2014-2018     B.Sc. in Biological Science, Minor in Mathematics and Chemistry
                        Indiana University South Bend
2019-2026     PhD in Cell & Developmental Biology
                        University of North Carolina at Chapel Hill
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