I am a Cell & Developmental Biologist interested in studying organogenesis, neurovascular system & signaling during development to improve maturity and functionality of engineered tissue for disease modeling and transplantation.
I am currently a PhD candidate at the University of North Carolina at Chapel Hill, in the laboratory of Dr. Lori O’Brien, researching how renal nerve signaling impact kidney development. My predoctoral research is currently funded by a American Heart Association (AHA) Predoctoral Fellowship.
I willl complement my understanding of kidney development, neurovascular patterning and developmental biology with postdoctoral training at the University of Pennsylvania under Dr. Alex Hughes where I will work on the kidney complex organisation and multicellular composition.
I am interested into the following questions:
I am currently a PhD candidate at the University of North Carolina at Chapel Hill, in the laboratory of Dr. Lori O’Brien, researching how renal nerve signaling impact kidney development. My predoctoral research is currently funded by a American Heart Association (AHA) Predoctoral Fellowship.
I willl complement my understanding of kidney development, neurovascular patterning and developmental biology with postdoctoral training at the University of Pennsylvania under Dr. Alex Hughes where I will work on the kidney complex organisation and multicellular composition.
I am interested into the following questions:
- How can we control patterning processes occurring during development to to synthetically reconstruct tissue patterning?
- How do we establish the correct vascular network (artery, capillary, arteriole and vein) with the correct structural characteristics (vascular fenestration, mural cell coverage, etc) at the proper level in complex 3D engineered organ?
- How can we promote neo-innervation (i.e. precise growth of neural network) with functional nerve-cell crosstalk during organogenesis to ensure proper function, tissue assimilation, and bio-regulation post-implantation?
- How can we leverage signaling molecules from neuro-vascular system and promote proper tissue development and organization?
- How does extracellular matrix and mechanical force participates in proper morphogenesis in engineered organ?